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Background
Although provider‐level volume is frequently associated with outcomes in cancers requiring complex surgeries, whether similar relations exist for cancers treated primarily with systemic therapy is unknown.
Methods
Using a population‐based cohort analysis of older adults diagnosed with diffuse large B cell lymphoma (DLBCL) during the years 2004‐2011, we evaluated the association between...
Background
Cancer costs should be discussed by patients and providers, but information is not readily available. Results from recently published studies (in the last 5 years) on direct and indirect cancer costs may help guide these discussions.
Methods
The authors reviewed studies published between 2013 and 2017 that reported direct health care costs and indirect (productivity losses) costs. The...
Background
To the authors’ knowledge, there is limited information regarding the long‐term risk of congestive heart failure (CHF) among patients with follicular lymphoma, a prevalent non‐Hodgkin lymphoma diagnosis among those aged >65 years, especially within the context of therapeutic exposures and preexisting comorbidities.
Methods
Using Surveillance, Epidemiology, and End Results–Medicare...
Background
Increasing demands on health care systems require patients to take on more active roles in their health. Effective self‐management has been linked to improved health outcomes, and evidence shows that effective self‐management is linked to health literacy (HL). HL is an important predictor of successful self‐management in other chronic diseases but has had minimal testing in cancer.
Methods...
Background
Children with acute lymphoblastic leukemia (ALL) have an increased risk of obesity and short stature. To the authors’ knowledge, data regarding patients treated on contemporary protocols without cranial irradiation are limited.
Methods
Changes in z scores for body mass index (BMI), height, and weight from the time of diagnosis to 5 years off therapy were evaluated using multivariable...
Background
The highly selective oral tropomyosin receptor kinase (TRK) inhibitor larotrectinib has demonstrated significant activity in adult and pediatric TRK fusion cancers. In the current study, the authors describe the clinical course of children with locally advanced TRK fusion sarcoma who were treated preoperatively with larotrectinib and underwent subsequent surgical resection.
Methods
A...
Background
It has been demonstrated that fecal immunochemical test (FIT) mailing programs are effective for increasing colorectal cancer (CRC) screening. The objectives of the current study were to assess the magnitude of uptake that could be achieved with a mailed FIT program in a federally qualified health center and whether such a program can be implemented at a reasonable cost to support sustainability...
Despite significant improvements in pediatric brain tumor therapy and outcome, too many children still die of disease, and too many survivors experience significant sequelae as a result of conventional therapies. The molecular characterization of pediatric brain tumors has afforded tremendous insight into the basic biology and clinical management of these deadly childhood diseases. Genomic, epigenomic,...
Background
Multicomponent, evidence‐based interventions are viewed increasingly as essential for increasing the use of colorectal cancer (CRC) screening to meet national targets. Multicomponent interventions involve complex care pathways and interactions across multiple levels, including the individual, health system, and community.
Methods
The authors developed a framework and identified metrics...
Background
The objective of this study was to evaluate an ongoing initiative to improve colorectal cancer (CRC) screening uptake in the New York State (NYS) Medicaid managed care population.
Methods
Patients aged 50 to 75 years who were not up to date with CRC screening and resided in 2 NYS regions were randomly assigned to 1 of 3 cohorts: no mailed reminder, mailed reminder, and mailed reminder + incentive...
Background
This report details the cost effectiveness of a non‐nurse patient navigation (PN) program that was implemented at the University of Chicago Medical Center to increase colonoscopy‐based colorectal cancer (CRC) screening.
Methods
The authors investigated the impact of the PN intervention by collecting process measures. Individuals who received navigation were compared with a historic cohort...
Background
The objectives of the current study were to assess changes in colorectal cancer (CRC) screening uptake and the cost‐effectiveness of implementing multiple evidence‐based interventions (EBIs). EBIs were implemented at 2 federally qualified health centers that participated in the Colorado Department of Public Health and Environment’s Clinic Quality Improvement for Population Health initiative...
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